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枸杞多糖对家兔动脉粥样硬化斑块组织结构的影响
引用本文:潘秀丽. 枸杞多糖对家兔动脉粥样硬化斑块组织结构的影响[J]. 牡丹江医学院学报, 2009, 30(6): 1-3
作者姓名:潘秀丽
作者单位:牡丹江医学院附属红旗医院,黑龙江,牡丹江,157011
摘    要:目的:探讨枸杞多糖对家兔动脉粥样硬化斑块组织结构的影响。方法:将30只健康雄性新西兰大白兔按体重随机分为三组:模型组,自然消退组,枸杞多糖组,每组10只。各组均先用高胆固醇饮食喂养十周,十周后模型组继续喂养高胆固醇饮食,自然消退组喂养普通饮食,枸杞多糖组喂养普通饮食+50mg/kg,第二十周处死全部实验动物取主动脉胸部做HE染色,sma免疫组化染色,masson染色,进行病理分析和数据统计。结果:枸杞多糖组与自然消退组比较,斑块面积更小(P〈0.05),sma含量更少(P〈0.05),胶原纤维与弹性纤维的比例接近正常(P〈0.05)。结论:枸杞多糖能够减轻高脂饮食家兔动脉粥样硬化斑块的病变,改变其组织结构,进而增强动脉粥样硬化斑块的稳定性。

关 键 词:家兔  动脉粥样硬化斑块  枸杞多糖  平滑肌  纤维

THE EFFECTS OF LYCIUM BARBANUM POLYSACCHARIDE ON THE ORGANIZATIONAL STRUCTURE IN RABBIT ARTERIOSCLEROSIS PLAQUE
Pan Xiuli. THE EFFECTS OF LYCIUM BARBANUM POLYSACCHARIDE ON THE ORGANIZATIONAL STRUCTURE IN RABBIT ARTERIOSCLEROSIS PLAQUE[J]. Journal of Mudanjiang Medical College, 2009, 30(6): 1-3
Authors:Pan Xiuli
Affiliation:Pan Xiuli (Hongqi Hospital,Mudanjiang Medical College Mudanjiang Heilongjiang 157011)
Abstract:Objective:Discuss influence of Chinese matrimony-vine polysaccharide on domestic rabbit atherosclerosis mottling organizational structure.Methods:30 healthy male New Zealand big white rabbits were Divide into three groups stochastically according to the body weight: Model group,nature retrogression group,Chinese matrimony-vine polysaccharide group,each group contsining ten.Each group first uses the high cholesterol diet to feed for ten weeks,ten weeks later the model group continues to feed the high cholest...
Keywords:家兔  动脉粥样硬化斑块  枸杞多糖  平滑肌  纤维
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