精神分裂症患者“药物自我处置程式”训练的研究 |
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引用本文: | 张玲,谢焱,何芬兰,张进祥,蒋春雷.精神分裂症患者“药物自我处置程式”训练的研究[J].中国医学文摘:老年医学,2009(10):1017-1020. |
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作者姓名: | 张玲 谢焱 何芬兰 张进祥 蒋春雷 |
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作者单位: | 南宁心理医院临床心理科,广西530001 |
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基金项目: | 广西医疗卫生自筹经费课题(合同号:Z2007337)致谢:本研究"药物自我处置程式"训练得到北京回龙观医院崔勇副主任医师的指导 |
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摘 要: | 目的探讨“药物自我处置程式”训练对精神分裂症患者治疗依从性、社会功能和生活质量的影响。方法将66例住院非急性期精神分裂症患者随机分为训练组(n=33)和对照组(n=33)。在抗精神病药物治疗不变的前提下,训练组按照Liberman编写的“药物自我处置程式”进行分组训练8周,8周后两组随访6个月。采用自制的药物依从性评分表、社会功能缺陷量表(SDSS)、生活质量综合评定问卷(CQOLI-74)对两组患者进行评估。结果8周及随访6个月后训练组治疗依从性、SDSS总分、GQOLI-74总分较对照组显著提高(P〈0.01、P〈0.05)。同组不同时点比较,训练组8周及随访6个月患者治疗依从性、SDSS总分、GQOLI-74总分等较入组时有显著提高(P〈0.01或P〈0.05);两组随访6个月的治疗依从性下降,且与8周时的差异有统计学意义(P〈0.01)。相关分析显示,在8周和随访6个月后,患者GQOLI-74总分与SDSS总分、治疗依从性呈负相关,SDSS总分与治疗依从性呈正相关(P〈0.01)。结论“药物自我处置程式”训练能提高患者的治疗依从性,改善其社会功能,提高其生活质量。
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关 键 词: | 精神分裂症 药物自我处置程式 社会功能 生活质量 治疗依从性 |
Study on medication self-management module for patients with schizophrenia |
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Institution: | ZHANG Ling, XIE Yan, HE Fen-lan, et al.( Department of Clinical Psychology, the Nanning Psychology Hospital, Guangxi 530001, China) |
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Abstract: | Objective To explore the impact of medication self-management module on treatment compliance, social function and quality of life of patients with schizophrenia. Methods Sixty-six inpatients with schizophrenia in non-acute stage were randomly divided into training group( n = 33 ) and control group( n = 33 ). Both groups received the anti-psychotics therapy. Medication self-management module was only given to the training group for 8 weeks. All patients were followed up for 6 months and were evaluated with self-made drug treatment compliance rating scale, social disability screening schedule (SDSS), generic quality of life inventory-74 (GQOLI-74). Results Treatment compliance, the total scores of SDSS and the total scores of GQOLI-74 of training group were signifieanfly higher than those of control group after 8 weeks and 6 months( P 〈 0. 01, P 〈 0. 05 ). Treatment compliance, the total scores of SDSS and the total scores of GQOLI-74 of training group after 8 weeks and 6 months were significantly higher than those of pretraining(P 〈 0. 05 ). Treatment compliance of both groups on 6 months follow up were significantly lower than that of 8 weeks ( P 〈 0.01 ). Correlation analysis confirmed negative relation between the total scores of GQOLI-74 and the total scores of SDSS, treatment compliance, and confirmed positive relation between the total scores of SDSS and treatment compliance on 8 weeks and 6 months ( P 〈 0. 01 ). Conclusion Medication self-management module could significantly improve treatment compliance, social function and quality of life of patients with schizophrenia. |
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Keywords: | Schizophrenia Medication self-management module Social function Quality of life Treatment compliance |
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