帕金森病患者的睡眠障碍研究进展

帕金森病睡眠障碍目前尚无国际公认的分类标准,国外的学者倾向于将其分为失眠、快速动眼(REM)睡眠行为障碍、日间睡眠过多、睡眠发作4种类型。而帕金森病本身对睡眠中枢结构及递质的影响,帕金森病的运动症状,帕金森病的治疗和精神症状,以及自主功能失调、基因突变等均可影响睡眠。该文阐述了帕金森病非运动并发症睡眠障碍的类型、病因和发病机制,帕金森病睡眠障碍基本的治疗策略,以提高临床医生对帕金森病睡眠障碍的认识,改善帕金森病患者的生活质量。

Research Progress on Sleep Disorders in Patients with Parkinson Disease

The classification of sleep disorders in Parkinson disease has no international criterion at present.However,the foreign scholars incline to classify them into four types: insomnia,rapid eye movement behaviour disorder,excessive daytime sleepiness and sleep attacks.The sleep disorders in Parkinson disease are influenced by the disease's disturbance on the sleep central structures and transmitters,the Parkinson motor symptoms,the treatment-related and the psychiatric symptoms,the autonomic dysfunction and gene mutation and so on.To review types,the etiology,pathogenesis,the clinical major strategics of treatment of sleepiness in Parkinson disease,which is an To improve the recognition of clinicians for sleep disorders in Parkinson disease and the quality of life of the patients,the non-motor complications of Parkinson disease,including the types,the etiology,the pathogenesis and the clinical strategies of treatment,is reviewed.