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| 间质肉芽肿性皮炎 | |
| 引用本文： | 马东来,冯景春,方凯. 间质肉芽肿性皮炎[J]. 临床皮肤科杂志, 2008, 37(9): 559-561 |
| 作者姓名： | 马东来 冯景春 方凯 |
| 作者单位： | 中国医学科学院、中国协和医科大学北京协和医院皮肤科,北京,100730;中国医学科学院、中国协和医科大学北京协和医院皮肤科,北京,100730;中国医学科学院、中国协和医科大学北京协和医院皮肤科,北京,100730 |
| 摘 要： | 报告1例间质肉芽肿性皮炎。患者女，17岁。因左胸部和左上肢出现呈带状分布、无自觉症状的丘疹和结节半年就诊。免疫学检查示类风湿因子阳性。组织病理检查显示真皮间质和血管周围弥漫而致密的以组织细胞为主的炎性细胞浸润，部分组织细胞核大，有异形：炎性浸润细胞中还有中性粒细胞和少量淋巴细胞、浆细胞、多核巨细胞，局部可见灶性胶原纤维变性、坏死，未见嗜酸性粒细胞浸润和血管炎改变。阿新蓝染色阴性。免疫组化染色示CD68强阳性，S-100蛋白、AE1／AE3、SMA、结蛋白、LCA、CD45RO、CD20、CD21、CD23、CD31、CD34、CD1a和Ki-67均阴性。符合间质肉芽肿性皮炎的诊断。 |
| 关 键 词： | 皮炎 间质肉芽肿性 栅栏状嗜中性 肉芽肿性 |
Interstitial granulomatous dermatitis:a case report |
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| MA Dong-lai,FENG Jing-chun,FANG Kai. Interstitial granulomatous dermatitis:a case report[J]. Journal of Clinical Dermatology, 2008, 37(9): 559-561 | |
| Authors: | MA Dong-lai FENG Jing-chun FANG Kai |
| Affiliation: | Department of Dermatology;Peking Union Medical College Hospital;Chinese Academy of Medical Sciences and Peking Union Medical College;Beijing 100730;China |
| Abstract: | A 17-year-old girl presented with an asymptomatic linear papular and nodular eruptions on her left chest and left upper arm. Serologic test showed positive rheumatoid factor. Histopathologic examination revealed a dense diffuse interstitial and perivascular inflammatory infiltration, composed mostly of histiocytes. Some of these histiocytes had a large and atypical nuclei. Neutrophils, lymphocytes, plasma cells, scanty multinucleate giant cells and focal collagen necrosis were also present in the infiltrati... |
| Keywords: | dermatitis interstitial granulomatous palisaded neutrophilic and granulomatous |
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