高原地区青中年人群睡眠与慢性病共病的关联

目的  探讨高原地区青中年人群睡眠时长、睡眠质量、睡眠打鼾和慢性病共病的关联。方法  2018年5月―2019年8月采用多阶段随机整群抽样方法抽取拉萨市城关区30岁及以上人群进行问卷调查，采用多因素Logistic回归分析模型分析睡眠与慢性病共病之间的相关性。结果  共纳入5 505名30~ < 60岁青中年人，年龄为(44.70±8.50)岁，慢性病共病者占29.5%。多因素Logistic回归分析模型显示，在调整潜在混杂因素后，睡眠时长过短、睡眠质量差和睡眠打鼾是青中年人群慢性病共病的危险因素。与睡眠时长8 h相比，睡眠时长≤6 h者慢性病共病的OR值为1.57(95% CI: 1.21~2.04)；与睡眠质量好者相比，睡眠质量差者慢性病共病的OR值为1.59(95% CI: 1.39~1.82)；与睡眠时不打鼾者相比，睡眠时偶尔打鼾和经常打鼾者慢性病共病的OR值为1.20(95% CI: 1.02~1.41)和1.64(95% CI: 1.37~1.97)。结论  睡眠时长过短(≤6 h)、睡眠质量差和睡眠打鼾与高原地区青中年人群慢性病共病风险相关。高原地区青中年人群不仅要保证适宜的睡眠时间，而且要控制睡眠打鼾行为，提高睡眠质量。

Association of sleep with chronic comorbidities of young and middle-aged people in a plateau area

  Objective  To investigate the relationship of sleep duration, sleep quality, and snoring with chronic comorbidities in young and middle-aged people at high altitude.  Methods  From May 2018 to August 2019, people aged 30 and above in Chengguan District of Lhasa City were selected by multi-stage random cluster sampling method for questionnaire survey. Multivariate Logistic regression model was used to analyze the correlation between sleep and chronic comorbidities.  Results  A total of 5 505 young and middle-aged people aged 30-59 years old were included in the study. The average age was (44.70 ± 8.50) years old, and 29.5% of them were defined with chronic comorbidities. Multivariate Logistic regression models showed that shorter sleep duration, poor sleep quality, and snoring were risk factors for chronic comorbidities in young and middle-aged people after adjusting for potential confounding factors. Compared with participants with 8 hours of sleep duration daily, the OR (95% CI) of chronic comorbidities for those with sleep duration ≤6 h was 1.57(95% CI: 1.21-2.04). The OR (95% CI) of chronic comorbidities was 1.59(95% CI: 1.39-1.82) in the poor sleep quality group compared with those with good sleep quality. Compared with those who did not snore during sleep, the OR (95% CI) of chronic comorbidities in those who snored occasionally and frequently during sleep were 1.20 (95% CI: 1.02-1.41) and 1.64 (95% CI: 1.37-1.97), respectively.  Conclusions  Shorter sleep duration (≤6 h), poor sleep quality, and snoring are associated with chronic comorbidities in young and middle-aged people at high altitude. The middle-aged people in plateau area should not only ensure the proper sleep time, but also control the snoring behavior and improve the sleep quality.