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| 痛风及高尿酸血症药物治疗研究进展 | |
| 引用本文： | 聂颖,王文军. 痛风及高尿酸血症药物治疗研究进展[J]. 长春中医药大学学报, 2014, 0(5): 962-964 |
| 作者姓名： | 聂颖 王文军 |
| 作者单位： | 吉林市疾病预防控制中心;吉林市卫生局; |
| 摘 要： | 目前原发性痛风尚不能根治,主要通过药物治疗来控制血尿酸在360μmol/L以下、伴痛风石患者血尿酸控制在238μmol/L。目前常用的治疗药物主要包括作用于中性粒细胞治疗急性痛风的秋水仙碱、选择性与非选择性环氧化酶抑制剂、非甾体类抗炎药、糖皮质激素、黄嘌呤氧化酶（XO）抑制剂、别嘌醇等。 |
| 关 键 词： | 痛风 高尿酸血症 秋水仙碱 |
Progress of drug therapy for gout and hyperuricemia |
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| Affiliation: | NIE Ying, WANG Wenjun(1. Jilin Center for Disease Control and Prevention, Jilin 132001 ,Jilin Province, China; 2. Jilin Health Bureau, Jilin 132011, Jilin Province, China) |
| Abstract: | Currently, primary gout still cannot be cured, for which the blood uric acid is controlled to be less than 360 μmol/ L mainly by drug therapy while for patients with gouty tophus the blood uric acid is controlled to be less than 238 μmol/L. So far, frequently-used drugs are mainly colchicines that treating acute gout by acting on neutrophile granulocyte, selective and non-selective cyclooxygenase inhibitor-nonsteroidal anti-inflanunatory drugs （NAIDS）, glucocorticoids and xanthine oxidase （XO） inhibitor-allopurinol, etc. |
| Keywords: | gout hyperuricernia colchicine |
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