Duodenal diverticulosis in autosomal dominant polycystic kidney disease. |
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| Authors: | Sumedha Kumar Magdalena Adeva Bernard F King Patrick S Kamath Vicente E Torres |
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| Affiliation: | Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. |
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| Abstract: | ![]()
| Introduction | Autosomal dominant polycystic kidney disease (ADPKD) accountsfor approximately 5% of end-stage renal disease (ESRD) in USAand Europe. It is a systemic disease with multiple extrarenalmanifestations, including colonic diverticulosis. Diverticulitisand diverticular perforation contribute to the morbidity andmortality of ADPKD. Whether extracolonic diverticulosis is associatedwith ADPKD is uncertain. We report a series of eight ADPKD patientswith duodenal diverticulosis. In the index case, the clinicalpresentation was symptomatic diverticular disease. Case reports | A 72-year-old white woman on haemodialysis for 6 years for end-stageADPKD, presented with a weight loss of 40 pounds. She had experiencedepisodes of emesis, mostly 34 h post-prandially, forapproximately 1 year and diarrhoea for the past 6 months.
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| Keywords: | autosomal dominant polycystic kidney disease duodenal diverticulosis |
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