| 病毒性脑炎、脑膜炎多病原的探讨 |
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| 引用本文： | 孙景辉. 病毒性脑炎、脑膜炎多病原的探讨[J]. 临床儿科杂志, 2000, 18(2): 99-101 |
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| 作者姓名： | 孙景辉 |
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| 作者单位： | 孙景辉（白求恩医科大学一院儿科(130021)）;乔红梅（白求恩医科大学一院儿科(130021)）;傅文永（白求恩医科大学一院儿科(130021)）;张云峰（白求恩医科大学一院儿科(130021)） |
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| 摘 要： | 为探讨北主地区病毒性脑炎及脑膜炎的病原学构成，采用微量细胞培养法，应用人胚肺二倍体细胞（ＨＥＦ）、人表此样癌细胞（Ｈｅｐ－２）、猴肾传代细胞（Ｖｅｒｏ）及狗肾传代细胞（ＭＤＣＫ）等４种细胞系对８６例脑炎、脑膜为患儿的脑脊液、粪便及咽试标本进行了病毒分离。结果３６例分离到了病毒，阳性率为４１．８６＾（３６／８６例），其中肠道病毒３型（ＡｄＶ３）８例，单纯疱疹病毒１例（ＨＳＶ１）７例，阳性率分别为２０
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| 关 键 词： | 病毒性脑炎 脑膜炎 病原学 儿童 |
Study on etiological constitution in viral encephalitis and meningitis in children |
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| Sun Jinghui,Qiao Hongmei,Fu Wenyong,Zhang Yunfeng et al. Study on etiological constitution in viral encephalitis and meningitis in children[J]. The Journal of Clinical Pediatrics, 2000, 18(2): 99-101 |
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| Authors: | Sun Jinghui Qiao Hongmei Fu Wenyong Zhang Yunfeng et al |
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| Affiliation: | Sun Jinghui,Qiao Hongmei,Fu Wenyong,Zhang Yunfeng et al;(The Department of Pediatrics, the First Clinical Hospital affiliated to Norman Bethune University of Medical Science, Changchun 130021) |
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| Abstract: | To clarify the possible constitution of multiple pathogens in children with viral encephalitis and meningitis, viruses in the materials from CSF, faeces and throat swabs were isolated in 86 children with viral encephalitis and meningitis by using the way of micro-plate technique via four different susceptible cell lines of HEF, Hep-2, Vero and MDCK. The results showed that the positive culture appeared in 36 of 86 cases (41. 86%). Among them, enteroviruses could be discovered in 18 cases (20. 93%), adenovirus type 3 (AdV3) in 8 cases (9. 3%) and herpes simplex virus type 1 (HSV1) in 7 cases (8.14%). In addition, influ virus was seen in 2 cases and cytomegalovirus in 1 case. It is concluded that in etiological constitution of viral pathogens in children with viral encephalitis and meningitis, enterovirus might play an important role, and subsequently followed by AdV3 and HSV1. |
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| Keywords: | viral encephalitis viral meningitis etiology children |
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