| 紫外分光光度法测定尼美舒利栓的含量 |
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| 引用本文： | 高晓黎,陈新梅.紫外分光光度法测定尼美舒利栓的含量[J].中国药师,2003,6(5):277-278,285. |
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| 作者姓名： | 高晓黎 陈新梅 |
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| 作者单位： | 新疆医科大学药学院药剂学教研室,新疆,乌鲁木齐,830054 |
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| 基金项目： | 新疆特丰药业股份有限公司资助 |
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| 摘 要： | 目的 :建立用紫外分光光度法测定尼美舒利栓中尼美舒利的含量。方法 :用不同的有机溶剂萃取尼美舒利栓中的基质 ,用紫外分光光度法测定尼美舒利的含量。结果 :用正己烷作为萃取剂。用紫外分光光度法测定尼美舒利栓的含量 ,标准曲线线性好尼美舒利线性范围为 3～ 15 μg·ml-1(r =0 .9999)、回收率较好 (98.3% )。结论 :用紫外分光光度法测定尼美舒利栓剂的含量 ,方法简便、快速、结果准确 ,可作为尼美舒利含量测定的方法。
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| 关 键 词： | 尼美舒利栓 紫外分光光度法 含量测定 |
| 文章编号： | 1008-049X(2003)05-0277-03 |
Determination of Nimesulide in suppositories by UV Spectrophotometry |
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| Gao Xiaoli,Chen Xinmei.Determination of Nimesulide in suppositories by UV Spectrophotometry[J].China Pharmacist,2003,6(5):277-278,285. |
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| Authors: | Gao Xiaoli Chen Xinmei |
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| Abstract: | Objective: To establish a method for determination of nimesulide in suppositories. Methods: Screening different organic solution to extract the ground substrate in suppositories and determinating nimesulide by UV spectrophotometry. Results: N -Hexano was used as the solution of extraction. The method was very good for its good standard line( r = 0.9 999 ), high accuracy( RSD = 0.472% ) and high recovery( 98.3% ). Conclusion: This mehod is simple, rapid, and accurate. |
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| Keywords: | Nimesulide suppositories UV Spectrophotometry Content determination |
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