脑动脉狭窄的分布及影像学评估研究进展

我国10%～20%的缺血性卒中患者是由脑动脉狭窄所致，究其病因主要是动脉粥样硬化。
我国缺血性卒中患者颅内动脉粥样硬化性狭窄发生率高于颅外动脉。因此，颅内外动脉粥样硬化性
狭窄的早期诊断对预防卒中的发生具有重要临床意义。目前，磁共振血管成像（magnetic resonance
angiography，MRA）、高分辨率磁共振成像（high-resolution magnetic resonance imaging，HRMRI）、计算
机断层扫描血管造影（computed tomography angiography，CTA）、数字减影血管造影（digital subtraction
angiography，DSA）等影像学检查已广泛应用于颅内外动脉狭窄的评估。通过血管影像学显示狭窄分
布差异，从而探索卒中的发病机制已成为近些年研究的热点，本文就缺血性卒中患者的脑动脉狭窄
分布规律及影像学评估的研究进展情况做一综述。

Advance in Assessment of Cerebral Artery Stenotic Distribution by Neuroimaging

In China, 10%～20% patients with ischemic stroke are due to cerebral artery stenosis, which is mainly caused by atherosclerosis. Many studies have showed that intracranial artery stenosis is more frequent than extracranial artery stenosis in Chinese patients with ischemic stroke. Therefore, the early diagnosis of ex-intracranial artery stenosis is important to prevent the occurrence of cerebral infarction. Until recently, magnetic resonance angiography （MRA）, highresolution magnetic resonance imaging （HRMRI）, computed tomography angiography （CTA）, digital subtraction angiography （DSA） have been widely applied to assessment of ex-intracranial arterial stenosis. A hot topic in recent years is that by using neuroimaging to explore the etiology and pathogenesis of ischemic stroke according to cerebral artery stenotic distribution. In this article, we aimed to make a review of advance in the assessment of cerebral artery stenotic distribution by neuroimaging.