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| 光敏纳米脂质体制备及其特性研究 | |
| 引用本文： | 温演庆,杨斌,钱志勇,. 光敏纳米脂质体制备及其特性研究[J]. 中国医学工程, 2008, 16(2): 84-85 |
| 作者姓名： | 温演庆 杨斌 钱志勇 |
| 作者单位： | 1. 四川省出入境检验检疫局,四川,成都,600041 2. 四川大学华西医院生物治疗国家重点实验室,四川,成都,610041 |
| 摘 要： | 目的制备聚丁二炔光敏纳米脂质体并对其特性进行研究。方法采用反相蒸发法制备聚丁二炔纳米脂质体。原子力显微镜观察脂质体形态，激光粒度分析仪测定脂质体粒径与表面电位。结果制备的光敏纳米脂质体形状规则，平均粒径（78．3±1．4）nm。结论采用反相蒸发法制备的聚丁二炔纳米脂质体，达到设计要求。 |
| 关 键 词： | 丁二炔 纳米脂质体 |
Preparation and characterization of photosensitive liposomes |
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| WEN Yan-qing,YANG Bin,QIAN Zhi-yong. Preparation and characterization of photosensitive liposomes[J]. China Medical Engineering, 2008, 16(2): 84-85 | |
| Authors: | WEN Yan-qing YANG Bin QIAN Zhi-yong |
| Affiliation: | WEN Yan-qing1,YANG Bin1,QIAN Zhi-yong2(1.Sichuan Entry-Exit Inspection , Quarantine Bureau,Chengdu,610041,P.R.China,2.State Key Laboratory of Biotherapy,West China Hospital,West China Medical School,Sichuan University,P.R.China) |
| Abstract: | [Objective] To prepare photoallergic nano-liposeme containing polydiacetylene and to study its characteristics. [Methods] The liposome is prepared by reverse phase evaporation. Its morphous is observed by atomic force microscope, and its grain size and surface potential are determined. [Results] The figure of photoallergic nano-liposeme appears regulated and its nmean diameter is （78.3±1.4） nm. The nano-fiposome can be conserved over 18 months under 4℃. [ Conclusion] The photoallergie nano-liposome prepared by reverse phase evaporation achieves request of design. |
| Keywords: | diacetylene nano-liposome |
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