乳腺叶状肿瘤临床病理分析

目的探讨乳腺叶状肿瘤的病理特征、诊断、鉴别诊断以及与治疗和预后的关系。方法对经病理证实的52例乳腺叶状肿瘤患者的临床资料进行回顾性临床病理分析。结果52例中良性42例,交界性8例,恶性2例,均为女性,发病平均年龄40．8岁。病理特征：肿瘤大小不等,切面呈分叶状。组织学表现为良性的腺上皮和不同异型性的间质成分混合组成。结论乳腺叶状肿瘤的确诊主要靠病理诊断,需与分叶状纤维腺瘤、巨纤维腺瘤、乳腺癌肉瘤和乳腺肉瘤等鉴别,交界性和恶性叶状肿瘤易复发和转移,临床目前主要是以手术切除为主要治疗方法。

Clinical and pathological analysis of breast phyllodes tumor

Objective To investigate the pathological features, diagnosis, differential diagnosis of phyllodes tumor and the relationship between treatment and prognosis. Methods The clinical data of 52 cases of breast phyllodes tumors confirmed by pathology were retrospectively reviewed with clinical and pathologic analysis. Results Forty - two cases of benign, borderline in 8 cases, malignant in 2 eases, all were female, mean age was 40. 8 years. Pathological features ： tumor size was different and cut surface was lobulated. Histology showed benign glandular epithelium and stroma of different shaped components of a mixture. Conclusions The diagnosis of breast phyllodes tumors depends mainly on the pathological diagnosis, need to be differentiated from lobulated fibroadenoma, giant fibroadenoma, breast, sarcoma and breast sarcoma, the recurrence and metastasis of borderline and malignant phyllodes tumor is easy, surgical excision was the main treatment in chinic.