| 氟比洛芬酯脂微球注射液对38例癌症疼痛镇痛效果的临床观察 |
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| 引用本文： | 欧阳学农,王文武,彭永海,余宗阳,张霞.氟比洛芬酯脂微球注射液对38例癌症疼痛镇痛效果的临床观察[J].福州总医院学报,2006,13(3):142-143. |
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| 作者姓名： | 欧阳学农 王文武 彭永海 余宗阳 张霞 |
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| 作者单位： | 福州总医院肿瘤科，福州总医院肿瘤科，福州总医院肿瘤科，福州总医院肿瘤科，福州总医院肿瘤科 |
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| 摘 要： | 目的：观察氟比洛芬酯脂微球载体注射液（商品名凯纷）治疗癌痛的疗效和副作用。方法：38例未使用阿片类药物的中重度癌性疼痛患者每天静脉注射50mg/5ml氟比洛芬酯脂微球载体注射液．分别就其疗效、生活质量改善情况以及不良反应等方面进行评价。结果：氟比洛芬酯脂微球载体注射液治疗中重度癌痛的有效率为71．05％．生活质量改善情况治疗前后有显著差异（P〈0．05）。但未见一般非甾体类药物常见腹痛、消化道出血等副作用；也未见便秘、恶心、呕吐、嗜睡等阿片类药物常见不良反应。结论：氟比洛芬酯脂微球载体注射液治疗中重度癌痛疗效可靠．生活质量可得到改善．但氟比洛芬酯脂微球载体注射液不良反应发生率较低，可部分作为临床候选药品或口服吗啡替代药。
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| 关 键 词： | 氟比洛芬酯 脂微球 癌症疼痛 镇痛作用 |
STUDY ON THE ANALGESIC EFFECT OF FLURBIPROFEN AXETIL INJECTION ON PAIN IN ADVANCED CANCER |
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| Ou Yang Xuenong, Wang Wenwu, Peng Yonghai,et al..STUDY ON THE ANALGESIC EFFECT OF FLURBIPROFEN AXETIL INJECTION ON PAIN IN ADVANCED CANCER[J].Journal of Fuzhou Genenal Hospital,2006,13(3):142-143. |
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| Authors: | Ou Yang Xuenong Wang Wenwu Peng Yonghai |
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| Institution: | Ou Yang Xuenong, Wang Wenwu, Peng Yonghai, et al. Department of Oncology, Fuzhou General Hospital, Nanjing Military Command, Fuzhou, 350025. |
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| Abstract: | Objective:To observe the analgesic effect of flurbiprofen axetil injection in treatment of middle and severe pain in cancer patients.Method:The study was conducted in 38 case cancer patients.They were allocated to receive 50mg/5mL/day of flurbiprofen axetil injection for 2 weeks.Rusults:A total effective rate of 71.05% were achieved.In the study we did not observe the severe adverse reaction of flurbiprofen axetil injection.Conclusion:Flurbiprofen axetil injection was effective for middle and sev- er pain in cancer,its side effect were slight. |
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| Keywords: | Flurbiprofen axetil injection Lipid microspheres Carcinous pain Analgsic effect |
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