超鞭毛虫所致呼吸道感染的临床分析

目的探讨超鞭毛虫在下呼吸道感染中的临床意义。方法分析16例超鞭毛虫感染患者的临床资料、胸部影像学表现、纤维支气管镜和病原学检查结果。结果 16例下呼吸道超鞭毛虫感染患者中,发热16例,咳嗽15例,盗汗12例,喘息3例。血嗜酸粒细胞增高3例。16例均在呼吸道分泌物中查见活超鞭毛虫,8例呼吸道分泌物细菌培养阳性。胸部影像学以肺部多叶段渗出性斑片影或大片叶段实变影伴周围局限性模糊斑片影多见。纤维支气管镜检查可见有管腔内急性炎症反应的表现。甲硝唑治疗患者预后良好。结论下呼吸道感染病例的超鞭毛虫检测在广东深圳地区具有一定的临床意义,感染者以下呼吸道感染和混合感染为主。

Clinical Analysis of Lower Respiratory Tract Infection Caused by Hypermastigote

Objective To investigate the clinical features of lower respiratory tract infection caused by hypermastigote.Methods The clinical manifestations,chest imaging characteristics,fiber bronchoscopic and etiological test results were analyzed in 16 patients with hypermastigote infection in lower respiratory tract.Results In 16 patients with hypermastigote infection in lower respiratory tract,fever were present in all the cases,cough in 15 cases,night sweat in 12 cases,wheezing in 3 cases,and eosinophilia in 3 cases.Alive hypermastigotes were found in respiratory tract secretion in all the 16 cases.Bacterial culture of respiratory tract secretion yielded positive results in 8 of 16 cases.Chest imaging showed infiltrations in several lobes and segments or a large opacity with fuzzy patches.Bronchoscopy showed an acute inflammation in the respiratory tract lumen.Prognosis was good with the therapy of Metronidazole.Conclusions Detection of hypermastigote infection in lower respiratory tract have a definite clinical significance in Shenzhen area.Mixed infection is common in hypermastigote infection of lower respiratory tract.