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实验性急性胰腺炎时胰腺细胞膜流动性的变化及茵陈蒿汤的影响
引用本文:贾玉杰,钱迅,裴德恺. 实验性急性胰腺炎时胰腺细胞膜流动性的变化及茵陈蒿汤的影响[J]. 中国中西医结合外科杂志, 1997, 0(3)
作者姓名:贾玉杰  钱迅  裴德恺
作者单位:大连医科大学
摘    要:
本文以去氧胆酸钠诱发大鼠急性胰腺炎,就茵陈蒿汤及其组分对胰腺炎时胰腺细胞膜流动性的影响进行了观察。结果表明:急性胰腺炎早期,大鼠胰腺细胞总膜、线粒体膜和溶酶体膜流动性明显降低;茵陈蒿汤及其组分大黄和栀子可使其流动性接近正常。表现为大黄和栀子分别可提高总膜、溶酶体和线粒体膜的流动性;而茵陈蒿汤则主要提高溶酶体膜的流动性。

关 键 词:急性胰腺炎  胰腺细胞膜流动性  茵陈蒿汤

Effects of YCHT and Its Components on the Membrane Fluidity of Acinar Cells of Pancreas in Rats with Acute Pancreatitis
Jia yujie,et al Dalian Medical College. Effects of YCHT and Its Components on the Membrane Fluidity of Acinar Cells of Pancreas in Rats with Acute Pancreatitis[J]. Chinese Journal of Surgery of Integrated Traditional and Western Medicine, 1997, 0(3)
Authors:Jia yujie  et al Dalian Medical College
Abstract:
In this study acute pancreatitis(AP)was induced in rats with sodium deoxycholate.The effefts of YCHT(Yin Chen Hao Tang)and its components on the memberane fluidity of acinar cells were observed. Results showed that in the early stage of AP,the fluidities of plasmalemma,mitochondrial and lysosomal memrane of acinar cells of rats were declined significantly.YCHT and its components Rheum palmatum(RP)and Gardenia Jasminoides(GJ) could make the fluidity nearly noraml.RPand GJ could improve the fluidity of plasmalememma,lysosmal and mitochondrial membrane respectively,while the effect of YCHT seemed mainly to increase the membrane fluidity of lysosome.
Keywords:acute pancreatitis  membrane fluidity  Yin Chen Hao Tang
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