螺内酯治疗慢性心力衰竭疗效观察

目的探讨螺内酯治疗慢性心力衰竭的疗效。方法46例心力衰竭患者随机分为对照组和观察组各23例,对照组常规运用利尿剂、血管扩张剂和洋地黄制剂,观察组在对照组基础上加用螺内酯,2组均治疗1个月后,对治疗效果进行评价。结果2组治疗后心功能Ⅰ、Ⅱ级患者比率均增加,Ⅲ、Ⅳ级比率均降低,差异均有统计学意义（P〈0．05或P〈0．01）,观察组心功能改善情况优于对照组,差异均有统计学意义（P〈0．05）。结论螺内酯治疗慢性心力衰竭疗效确切,值得临床推广应用。

The effect observation of spironolactone in chronic heart failure curative

Objective To discuss the efficacy of spironolaetone in chronic heart failure treatment. Methods 46 cases of heart failure patient were divided into control group and the observation group,23 eases of each. The control group was given convention utilization diuretic, blood vessel relaxant and digitalis preparation, the observation group based on the control group was added with the spirono laetones,the two groups of patients in treat 1 month-long time, carried on the appraisal to the treatment result. Results Compared with those before treatment, the two groups of cardiac function after treatment for patient rates with Ⅰ, Ⅱ -grade increased, but readueced for Ⅲ, if-grade, the differences were statistically significant （P 〈 0.05 or P 〈 0. 01 ）, and the observation group were better than the control group, the differences were also statistical significant（ P 〈 0.05 ）. Conclusion Spironolaetone＇s in treatment chronic heart failure curative effect more accurate satisfaction, is worth promoting and the application.