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新疆地区SEN病毒的感染状况
引用本文:帅金志,郭二兵,白旭华. 新疆地区SEN病毒的感染状况[J]. 农垦医学, 2007, 29(4): 260-262
作者姓名:帅金志  郭二兵  白旭华
作者单位:石河子大学医学院,新疆石河子,832002;新疆兵团中心血站,新疆乌鲁木齐,830000
摘    要:目的:研究新疆地区部分人群SEN病毒(SENV)感染状况.方法:以SENV读码框架1区(ORF1)核苷酸序列设计引物建立巢式聚合酶链反应(nPCR)方法,采用多重nPCR对295份来自4种不同人群血标本进行SENV-DNA(D和H亚型)分析.结果:SENV的感染率为40%,4种人群中SENV感染率的高低依次为乙肝表面抗原阳性者(51.3%)、HCV阳性者(36 .8%)、健康献血人群(35.7%)、单纯ALT升高者(14.8%).结论:新疆地区不同人群中存在较高的SENV感染率.

关 键 词:SEN病毒  巢式PCR  感染率

Prevalence of SEN Virus Infection in Xinjiang Area
Shuai Jinzhi,Guo Erbing,Bai Xuhua. Prevalence of SEN Virus Infection in Xinjiang Area[J]. Agricultural Reclamation Medicine, 2007, 29(4): 260-262
Authors:Shuai Jinzhi  Guo Erbing  Bai Xuhua
Affiliation:1. 2004 class Master postgraduate in Shihezi University School of medicine,Xinjiang Shihezi, 832002
Abstract:Objective: To investigate the prevalence of SENV in Xinjiang area.Methods:Nested polymerase chain reaction(nPCR) was established using primers from ORF1 region of SENV genome.Two hundred and ninety five sera samples from four different populations were detected for SENV DNA(D and H subtype) by nPCR.Results:SENV-DNA positive Rate was 40%(118/295) totally,from which 51.3% in hepatitis B virus surface agent positive,36.8% in the hepatitis C virus positive,35.7% in the healthy blood donor,14.8% in alanine aminotransferase level higher than 30 IU/L respectively.Conclusion:The SENV infection rate was high in different populations in Xinjiang area.
Keywords:SEN virus(SENV)  nested-polymerase chain reaction(nPCR)  Prevalence
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