北京地区327例化妆品皮肤病临床调查及分析

目的 调查分析2006年北京地区化妆品皮肤不良反应的发生情况及特点.方法 以2006年1～12月间在北京空军总医院化妆品皮肤病专科门诊就诊患者为调查对象,以<化妆品皮肤病诊断标准及处理原则总则>中的7项化妆品皮肤病诊断国家标准(GB 17149.1～17149.7-1997)为诊断标准,用统一的登记表格记录化妆品皮肤病患者的年龄、性别、职业、病史资料和化妆品相关内容,并进行斑贴试验,汇总数据并进行统计分析.结果 共监测发现化妆品皮肤病患者327例,其中女性322例占98.47%,83.49%为21～40岁的中青年;涉及可疑化妆品14类925种,其中进口产品涉及47个品牌618种产品,占66.81%;国产及合资企业产品涉及43个品牌293种产品,占31.68%;美容院自制产品和"三无"14种,占1.51%;在所监测到的化妆品皮肤病中,化妆品接触性皮炎最多,共318例,占97.24%;化妆品痤疮7例,占2.14%;化妆品皮肤色素异常2例,占0.61%.结论 化妆品接触性皮炎是最常见的化妆品皮肤病,具有中高等文化程度、21～40岁的中青年女性公司职员,是化妆品皮肤病的高危发病人群.

Cosmetic dermatosis:clinical investigation and analysis of 327 cases in Beijing area

Objective To summarize the data of cosmetics dermatosis happened in Bering in 2006 and to analyze their characteristics of this side effect.Methors The outpatients in the Department of Dermatology.Air Force General Hospital from Jun.2006 to Dec.2006 were investigated and screened out the cosmetic dermatosis according to GB17149.1～7-1997,the patients'age,gender,job and the demographic data and the suspected cosmetics were recorded and analyzed,and the routine patch tests using the involved cosmetic products were carried out in each patient.Results 327 cases of cosmetic dermatosis were reported.Among all cases.98.47% of the patients were female,and most of them aged between 21 and 40 years old:The suspected cosmetics included 47 brands with 618 imposed products,43 brands with 293 domestic and the joint venture products,and 14 illegal products;Clinically,318 cases(97.24%)of the lesion were diagnosed as cosmetic contact dermatitis.7 acne and 2 skin discoloration.Conclusion Cosmetic contact dermatitis is the most common cosmetic dermatosis,and the young and middle-aged females with middle or high education are the most susceptible people to cosmetic dermatosis.