靳三针疗法治疗卒中后认知障碍的临床研究

目的:观察靳三针治疗卒中后认知障碍的临床疗效,以及对神经电生理(事件相关电位)的影响.方法:选取卒中后认知障碍患者60例,按照随机数字表法分为治疗组和对照组,每组30例.对照组患者予常规治疗,治疗组患者在常规治疗基础上加靳三针疗法,两组均连续治疗4周.比较治疗前后两组简易精神状态检查量表(MMSE)和蒙特利尔认知评估量表(MoCA)评分,以及P300波幅和潜伏期.结果:治疗前两组MMSE和MoCA评分、P300潜伏期和P300波幅差异均无统计学意义(均P>0.05).治疗4周后,两组MMSE和MoCA评分及P300波幅均较治疗前提高,P300潜伏期较治疗前缩短,组内及组间差异均有统计学意义(均P<0.05).结论:常规治疗基础上加靳三针疗法治疗卒中后认知障碍疗效可靠.其机制可能是通过调控患者的神经电生理改善患者的认知状态.

Clinical study on Jin's three-needle therapy for post-stroke cognitive impairment

Objective:To observe the clinical efficacy of Jin's three-needle therapy on post-stroke cognitive impairment(PSCI)and the effect on neuroelectrophysiology(event-related potentials).Methods:A total of 60 PSCI patients were selected and divided into a treatment group and a control group according to the method of random number table,with 30 cases in each group.The patients in the control group received routine treatment while the patients in the treatment group received additional Jin's three-needle therapy.The treatment for both groups lasted four weeks.Mini-mental state examination(MMSE)and Montreal cognitive assessment(MoCA)scores as well as amplitude and latency of potential 300(P300)were adopted to compare the between-group results before and after treatment.Results:Before treatment,there were no significant differences(all P>0.05)in MMSE and MoCA scores,P300 latency and P300 amplitude between the two groups.After 4 weeks of treatment,the MMSE and MoCA scores and P300 amplitudes were improved in both groups,and the P300 latencies became shorter.The results showed significant intra-group and between-group differences(all P<0.05).Conclusion:Based on the routine treatment,Jin's three-needle therapy is effective for PSCI.The mechanism is probably through its regulation on the patients'neuroelectrophysiology.