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Effects of Mediterranean Diet on plasma metabolites and their relationship with insulin resistance and gut microbiota composition in a crossover randomized clinical trial
Affiliation:1. Department of Biochemistry and Biotechnology, Faculty of Medicine and Health Sciences, University Rovira i Virgili (URV), Reus, Spain;2. Institute of Health Pere Virgili, IISPV, University Hospital Sant Joan, Reus, Spain;3. Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain;4. ABS Reus V. Centre d''Assistència Primària Marià Fortuny, SAGESSA, Reus, Spain;1. German Institute of Human Nutrition, Potsdam-Rehbrücke, Department of Nutrition and Gerontology, Nuthetal, Germany;2. University of Potsdam, Institute of Nutritional Science, Potsdam, Germany;3. Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Department of Geriatrics, Berlin, Germany;4. University of Potsdam, Institute of Nutritional Science, Department of Physiology and Pathophysiology of Nutrition Potsdam, Germany;5. German Institute of Human Nutrition, Potsdam-Rehbrücke, Department of Physiology of Energy Metabolism, Nuthetal, Germany;6. Institut für Humanernährung und Lebensmittelkunde, Christian-Albrechts-Universität zu Kiel, Kiel, Germany;1. Health Management Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China;2. Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China;3. Department of Blood Transfusion, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China;1. Department of Liver Surgery, Liver Transplantation Division, West China Hospital, Sichuan University, Chengdu, 610041, China;2. Laboratory of Liver Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China;3. Department of Hepatobiliary Pancreatic Tumor Center, Chongqing University Cancer Hospital, Chongqing, 400030, China;4. Department of Hepatic Surgery and Liver Transplantation Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510006, China;1. Pediatrics, University of Illinois College of Medicine at Peoria, Peoria, IL, United States;2. Nursing, OSF Saint Francis Medical Center, Peoria, IL, United States;3. Food & Nutrition, Food & Nutrition, OSF Saint Francis Medical Center, Peoria, IL, United States;4. Biostatistics, OSF Saint Francis Medical Center, Peoria, IL, United States;1. Department of General, Visceral and Thoracic Surgery, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany;2. Department of Diagnostic and Interventional Radiology and Nuclear Medicines, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany;3. Institute of Medical Biometry and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany;4. Department of Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany
Abstract:
Keywords:Mediterranean diet  Nuts  Insulin resistance  Plasma metabolome  Gut microbiota  CVD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0040"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cardiovascular disease  GC-QTOF-MS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  gas chromatography time-of-flight mass spectrometry  HOMA-IR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  homeostasis model assessment of insulin resistance  LC-Q-TOF-MS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  liquid chromatography quadrupole time-of-flight mass spectrometry  LC-QqQ-MS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  liquid chromatography with triple-quadrupole mass spectrometry  LPC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  lysophosphocholine  LPE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0100"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  lysophosphoethanolamine  MedDiet"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0110"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Mediterranean diet  MetS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0120"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  metabolic syndrome  PC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0130"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  phosphocholine  T2D"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0140"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  type-2 diabetes  TG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0150"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  triglyceride  TMA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0160"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  trimethylamine  TMAO"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0170"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  trimethylamine N-oxide  TCA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0180"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  tricarboxylic acid
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