垂体后叶素在腹腔镜下卵巢囊肿剥除术中的应用研究

目的探讨经腹腔镜行卵巢囊肿剥除术中垂体后叶素的使用价值。方法回顾分析经腹腔镜卵巢囊肿剥除术120例的临床资料,随机分为观察组和对照组各60例。观察组巧克力囊肿20例、畸胎瘤20例、卵巢单纯性囊肿20例,均为单侧。对照组巧克力囊肿20例、畸胎瘤20例、卵巢单纯性囊肿20例,也均为单侧。观察组分别于卵巢囊肿剥除前在正常卵巢皮质与囊肿壁间注射垂体后叶素稀释液（浓度15%）,然后行囊肿剥除术,对照组直接剥除。比较两组手术时间、术中出血量、囊肿破裂率、术后卵巢功能。卵巢功能的判断采取术前及术后月经恢复情况及术后3、6、12个月测定的卵泡刺激素（FSH）水平。结果观察组手术时间、术中出血量、术中肿块破裂率、术后月经恢复天数明显少于对照组（P〈0.05）,术后住院天数两组差异无统计学意义（P〉0.05）;术前和术后的FSH水平在对照组存在显著差异（P〈0.05）,在观察组差异不大（P〉0.05）。结论使用垂体后叶素注射分离法在腹腔镜下卵巢囊肿剥除术中能达到易于分离、较好止血及减少卵巢功能伤害。

Clinical analysis of vasopressin injection technique in laparoscopic ovarian cystectomy

Objective To evaluate the effects of vasopressin injection technique（ VIT） in laparoscopic operation in patients with ovarian cysts. Methods 120 patients with ovarian cysts were retrospectively studied. 60 patients were divided into experimental group with vasopressin injection technique. 60 ovary surgery patients by laparoscopy（ the single two stage electricity congeals hematischesis） were divided into control group. The operation time,the amount of bleeding,the ratio of ovarian cyst rupture in operation,the period between operation and next menstruation and postoperative hospitalization time were analyzed. FSH was determined before surgery and at 3-month,6 month,and 12-month follow-up after laparoscopic cystectomy. Results The operation time,the amount of bleeding and the ratio of ovarian cyst rupture in operation,menstruation recovery days after operation in experimental group were less obviously than those in control group（ P 0. 05）. But there was no significant difference in postoperative hospitalization time between two groups（ P 0.05）. The FSH levels were significantly different before and after surgery in control group（ P 0.05）,but not in experimental group（ P 0. 05）. Conclusion The vasopressin injection is a good ideal procedure in removing ovary cyst under laparoscopy. It may shorten the operation time,reduce the volume of blood bleed in operation,and then to safeguard the function of ovaries.