Short chain fatty acids in plasma and brain: quantitative determination by gas chromatography. |
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| Authors: | C Bachmann J P Colombo J Berüter |
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| Affiliation: | Department of Clinical Chemistry, Inselspital, University of Berne, 3010 Berne Switzerland |
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| Abstract: | ![]()
A reliable and practicable method for the determination of short chain fatty acids in plasma and brain tissue is presented. The sample preparation by partition chromatography on silicic acid allows subsequently a quantitation of short chain fatty acids without interference by methylmalonic acid, or other more polar compounds. With the gas-chromatographic system 2-methylbutyrate is separated from isovalerate. Reference values are given for plasma. The system is also useful in combination with mass spectrometry. |
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| Keywords: | To whom correspondence should be addressed. |
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