|
|||||
|
|
| 创伤性脑损伤后大鼠皮质AQP4表达的变化 | |
| 引用本文： | 李慢,喻博,罗斐斐,石玉秀,李花. 创伤性脑损伤后大鼠皮质AQP4表达的变化[J]. 解剖科学进展, 2011, 17(1): 12-15 |
| 作者姓名： | 李慢 喻博 罗斐斐 石玉秀 李花 |
| 作者单位： | 中国医科大学,基础医学院,组织学与胚胎学教研室,辽宁,沈阳,110001 |
| 基金项目： | 辽宁省教育厅科学技术研究项目(No.2008779,2008851) |
| 摘 要： | 目的 观察创伤性脑损伤后大鼠皮质水通道蛋白4(aquaporin4,AQP4)表达的变化.方法 采用Feency法建立脑损伤大鼠模型,取成年健康雄性wistar大鼠60只,随机分为6组,So、S1、S4、S1W、S2W及正常对照组.采用免疫组化和免疫印迹方法进行各组AQP4表达变化的观察及检测,进行图像分析和统计学处理... |
| 关 键 词： | 创伤性脑损伤 AQP4 皮质 大鼠 |
Expression alteration of aquaporin 4 in cortex of the traumatic brain injury rats |
|
| LI Man,YU Bo,LUO Fei-fei,SHI Yu-xiu,LI Hua. Expression alteration of aquaporin 4 in cortex of the traumatic brain injury rats[J]. Progress of Anatomical Sciences, 2011, 17(1): 12-15 | |
| Authors: | LI Man YU Bo LUO Fei-fei SHI Yu-xiu LI Hua |
| Affiliation: | LI Man,YU Bo,LUO Fei-fei,SHI Yu-xiu,LI Hua (Department of Histology and Embryology,China Medical University,Shenyang 110001 China) |
| Abstract: | Objective To observe the expression of aquaporin 4 (AQP4) in cortex of the traumatic brain injury rat. Methods The Feency method was used to set up the rat models. A total of 60 male Wistar rats were randomly divided into S0, S1, S4, S1W, S2W and normal control group. The expression of AQP4 was detected using immunohistochemistry, western blotting, image analysis and statistical analysis. Result Compared to control group, expression levels of AQP4 gradually increased at S0, peaked at S1, and then gradually ... |
| Keywords: | traumatic brain injury aquaporin 4 cortex rat |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |