排放腹水前后血压变化与肝肾综合征的发生

目的探索肝硬化腹腔积液患者排放腹水前后动脉血压变化对肝肾综合征发生风险的影响。方法回顾性分析42例需长期反复排放腹水的肝硬化患者,按排放腹水后动脉血压降低幅度分组,比较2组间近期肝肾综合征发生率。结果腹水排放后动脉血压降低幅度〉10mmHg患者近期肝肾综合征发生率显著高于对照组（65.0%vs22.7%,P=0.012）。结论控制腹水排放量,维持患者有效循环血量有助于减少近期肝肾综合征发生风险。对大量排放腹水病人,及时补充有效循环血量或腹带约束可能有助于降低肝肾综合征发生率。

Association between Hepatorenal Syndrome and Decrease of Blood Pressure after Paracentesis

Objective To evaluate the impact of decrease of blood pressure after paracentesis on incidence of hepatorenal syndrome. Methods 42 patients with cirrhosis who need routine paracentesis were divided into two groups by blood pressure decrease range after paracentesis. Incidence of hepatorenal syndrome were calculated.Results Patients with the decrease of blood pressure lower than 10 mmHg has a higher incidence rate of hepatorenal syndrome than control（65.0%vs22.7%,P=0.012）.Conclusion To keep a effective circulatory blood volume through controlling emissions of ascites is beneficial to reduce hepatorenal syndrome.The incidence of hepatorenal syndrome may be decreased by resuming effective circulatory blood volume or bellyband pressure after paracentesis.