| 脊髓损伤后中枢性疼痛的实验模型和机制研究进展 |
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| 引用本文： | 谢永刚,张小洺,姚尚龙.脊髓损伤后中枢性疼痛的实验模型和机制研究进展[J].国际麻醉学与复苏杂志,2006,27(6):357-360. |
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| 作者姓名： | 谢永刚 张小洺 姚尚龙 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院麻醉科,武汉市,430022 |
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| 摘 要： | 中枢性疼痛(central pain,CP)是脊髓损伤(spi-nal cord injury,SCI)的顽固性合并症,为患者主观上感到损伤平面以下皮肤痛觉消失区一种以自发痛为主的疼痛,发生率为11%~94%,严重者为5%~30%。近年来其发生率逐年增高,使很多患者陷于抑郁、药物成瘾、甚至自杀的悲惨境地。许多疼痛
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| 关 键 词： | 中枢性疼痛 实验模型 脊髓损伤 injury 神经结构 疼痛综合征 SCI 皮肤痛觉 |
Advance in central pain following spinal cord injury |
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| XIE Yong-gang,ZHANG Xiao-ming,YAO Shang-long.Advance in central pain following spinal cord injury[J].international journal of anesthesiology and resuscitation,2006,27(6):357-360. |
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| Authors: | XIE Yong-gang ZHANG Xiao-ming YAO Shang-long |
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| Institution: | Department of Anesthesiology, Wuhan Union Hospital, Wuhan 430022, China |
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| Abstract: | Central pain(CP) following spinal cord injury challenges the health care community.A number of pain syndromes associated with spinal cord injury are based on the nature of the lesion,neurological structure damage and secondary pathophysiological changes.The treatment of these patients will remain the same as for any other type of pain if one does not understand the different mechanisms.So it is very important to study the mechanisms according to appropriate animal models. |
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| Keywords: | spinal cord injury central pain experimental models mechanisms |
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