Abstract: | If intact bone marrow is injected into mice at the peak of the secondary immune response, the number of antibody-forming cells in a regional lymph node is increased by 2.4 times. Preliminary injection of bone marrow into donors of cells of immune lymph nodes reduces the effect of stimulation of antibody formation during their subsequent combined culture with intact bone marrow cells. The results demonstrate interaction between cells at the level of mature antibody producers in vivo.Institute of Biophysics, Ministry of Health of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR P. D. Gorizontov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 85, No. 4, pp. 447–449, April, 1978. |