Continuous measurement of oxygen consumption using the reversed fick method |
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Authors: | Michihiko Fukui Maho Imoto Nobuaki Shime Tetsuo Hatanaka Hideaki Tojo |
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Institution: | (1) Intensive Care Unit, Otsu Municipal Hospital, 2-9-9 Motomiya, 520 Otsu, Shiga, Japan;(2) Department of Anesthesiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamiigyo-ku, 602 Kyoto, Japan |
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Abstract: | We developed a continuous oxygen consumption (Vo2) measurement system employed the reversed Fick method, in which Vo2 in computed from continuously measured sured arterial and mixed venous oxygen saturation assed by pulse oximetry and mixed
venous oximetry, respectively, and cardiac output by the heat deprivation technique. This system was compared with the conventional
intermittent reversed fick method in 7 patients during surgery and with indirect calorimetry in 4 intensive care unit (ICU)
patients. The Vo2 measured by the continuous reversed Fick method showed a high correlation with those simultaneously measured by the intermittent
Fick method (r=0.97,P<0.01) and by indirect calorimetry (r=0.74,P<0.01). The 95% confidence limits (bias±2 SD) of the continuous reversed Fick method were −0.6±45 ml·min−1 with the intermittent Fick method and −31±56 ml·min−1 with indirect calorimetry. The continuous Fick method is in satisfactory agreement with the conventional methods for the
measured of Vo2 and potentially allows for convenient assessment of Vo2 in critically ill patients.
This study was supported in part by Grants-in-Aid for the Encouragement of Young Scientists 01771185 and 04857171 from the
Ministry of Education, Science and Culture of Japan |
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Keywords: | Indirect calorimetry Monitor Pulse oximetry Shock Heat deprivation |
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