Coulter LH 750仪网织红细胞检测参数的临床价值分析

目的探讨BeckmanCoulterLH750全自动血液分析仪检测网织红细胞及其新型参数的方法及临床应用价值。方法用BeckmanCoulterLH750全自动血液分析仪检测248例住院贫血患者抗凝全血标本的网织红细胞百分比(RET％)、网织红细胞绝对值(RET#)、网织红细胞平均体积(MRV)、未成熟网织红细胞组分(IRF)、高散射光强度网织红细胞百分比(HLR％)等五项网织红细胞参数。结果慢性肾功能不全的贫血患者RET#同对照组比较无显著差异,但HLR％显著高于对照组(P<0.05)。失血性贫血的患者网织红细胞各项指标与对照组相比显著增高;肝硬化与正常对照组RET％、RET#和HLR％有显著差异(P<0.05)。结论测定网织红细胞及其相关参数有助于判断红细胞的活动度,对贫血类型的初筛诊断、治疗监测等有重要的实用价值。

The Applying of Reticulocyte and Its Parameters in an Anemia

Objective To study the clinical using of reticulocyte and its new parameters detected by Beckman Coulter LH 750 automatic blood analysor. Methods Reticulocyte percentage (RET%) ,reticulocyte absolute value (RET#) ,reticulocyte mean volume(MRV) ,immature reticulocyte formation(IRF) and high scattered light intensity reticulocyte percentage (HLR%) of 248 cases inpateients blood sample were detected by Beckman Coulter LH 750 automatic blood analysor. Results RET # in an anemia of chronic renal dysfunction showed no obvious difference compared with the control, but HLR% was notably higher than the control (P<0. 05). Every parameter in a posthemorrhagic anemia patient was remarkably higher than the control. RET%,RET# and HLR% in a hepatic cirrhosis patient showed marked difference(P<0. 05). Conclusion The detection of reticulocyte and its parameters is helpful to decide the activity of red blood cell,and it has important practical value in first consultation,treatment and monitoring of anemia type.