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Safety and Effectiveness of Ledipasvir and Sofosbuvir,With or Without Ribavirin,in Treatment-Experienced Patients With Genotype 1 Hepatitis C Virus Infection and Cirrhosis
Authors:Joseph K. Lim  Ann Marie Liapakis  Mitchell L. Shiffman  Anna S. Lok  Stefan Zeuzem  Norah A. Terrault  James S. Park  Charles S. Landis  Mohamed Hassan  Joel Gallant  Alexander Kuo  Paul J. Pockros  Monika Vainorius  Lucy Akushevich  Larry Michael  Michael W. Fried  David R. Nelson  Ziv Ben-Ari
Affiliation:1. Yale University School of Medicine, New Haven, Connecticut;3. Liver Institute of Virginia, Richmond, Virginia;4. University of Michigan, Ann Arbor, Michigan;6. J. W. Goethe University Hospital, Frankfurt, Germany;5. University of California-San Francisco, San Francisco, California;7. University of Washington, Seattle, Washington;12. University of Minnesota, Minneapolis, Minnesota;8. Southwest CARE Center, Santa Fe, New Mexico;10. Virginia Mason Medical Center, Seattle, Washington;9. Scripps Clinic, La Jolla, California;71. University of Florida, Gainesville, Florida;123. Sheba Medical Center, Ramat Gan, Israel
Abstract:
Keywords:Real World  Liver Disease  Viral Hepatitis  Therapy  HCV-TARGET  AE  adverse event  CI  confidence interval  DAA  direct-acting antiviral agent  EP  evaluable population  GT  genotype  HCC  hepatocellular carcinoma  HCV  hepatitis C virus  LDV  ledipasvir  MELD  Model for End-Stage Liver Disease  OLT  orthotopic liver transplantation  OR  odds ratio  PegIFN  pegylated interferon  PP  per protocol  RBV  ribavirin  SOF  sofosbuvir  SVR  sustained virologic response  TE  treatment-experienced
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