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| 先天性甲状腺功能低下症L—T4治疗的观察 | |
| 引用本文： | 杨箐岩 王秀英. 先天性甲状腺功能低下症L—T4治疗的观察[J]. 天津医科大学学报, 1997, 3(3): 25-26,32 |
| 作者姓名： | 杨箐岩 王秀英 |
| 作者单位： | [1]天津市内分泌研究所 [2]天津医科大学总医院儿科 |
| 摘 要： | 观察了２３例原用甲状腺片替代治疗的先天性甲状腺功能低下症（先天性甲低）患儿，改用国产左旋甲状腺素钠（Ｌ－Ｔ４）治疗前后的血清甲状腺激素水平的变化。服Ｌ－Ｔ４前１６例Ｔ３、ＦＴ３高于正常值；９例Ｔ４在正常低限；ＦＴ４除１例低于正常，均在正常范围，但其中７例为正常低值。采用Ｌ－Ｔ４后均恢复正常，有显著性差异（Ｐ〈０．０１），ＴＳＨ无明显差异。４例原为骨龄发育提前者，服Ｌ－Ｔ４两年后骨龄正常。提示Ｌ－Ｔ |
| 关 键 词： | 甲状腺功能低下 左旋甲状腺素钠 药物疗法 |
EVALUATION OF THE EFFECT OF L T4 (CHINESE PRODUCTS) ON CONGENITAL HYPOTHYROIDISM |
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| Yang Qingyan et al. EVALUATION OF THE EFFECT OF L T4 (CHINESE PRODUCTS) ON CONGENITAL HYPOTHYROIDISM[J]. Journal of Tianjin Medical University, 1997, 3(3): 25-26,32 | |
| Authors: | Yang Qingyan et al |
| Affiliation: | Institute of Endocrinology |
| Abstract: | Change of serum thyroid concentration and bone age were measured before and after treating by L T4 (Chinese products) in 23 cases with congenital hypothroidism that were given with thyroid tabets before Before treating by L T4,serum T3,FT3 were higher than normal range in 16 cases Serum T4 of 9 cases were at low limit of normal range Serum FT4 of all cases were at normal range but 1 case was lower 7 cases of all were at low limit of normal range T3,FT3,T4, and FT4 are restored to normal after treatment by L T4 It had a significant difference ( P <0 01) But TSH level were no obvious difference Bone age in 4 cases who had premature became normal after treating with L T4 for two years |
| Keywords: | Congenital hypothyroidism Thyroid hormone L T4 |
| 本文献已被 CNKI 维普 等数据库收录！ | |