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双侧原发性异时性乳腺癌ER、PR激素受体的表达及临床病理特征
引用本文:钟红,马斌林,王薇. 双侧原发性异时性乳腺癌ER、PR激素受体的表达及临床病理特征[J]. 新疆医科大学学报, 2007, 30(11): 1251-1253
作者姓名:钟红  马斌林  王薇
作者单位:新疆医科大学附属肿瘤医院乳腺外科,新疆,乌鲁木齐,830011
摘    要:目的:探讨双侧原发性异时性乳腺癌中雌激素受体(Estroganreceptor,ER)、孕激素受体(Progestinre-cetor,PR)表达情况及病理特征。方法:对2001-2006年收治的25例双侧原发性异时性乳腺癌进行ER、PR表达检测,并分析其病理学特征。结果:双侧原发性异时性乳腺癌第一原发癌中ER、PR阳性表达率分别为68%和56%,第二原发癌中ER、PR阳性表达率分别为60%和40%。浸润性导管癌在双侧异时性乳腺癌第一、二原发癌中分别占64%和52%。结论:双侧原发性异时性乳腺癌有较高的ER、PR表达,浸润性导管癌与双侧原发性异时性乳腺癌有明显关系。

关 键 词:双侧原发性异时性乳腺癌  雌激素受体(ER)  孕激素受体(PR)
文章编号:1009-5551(2007)11-1251-03
收稿时间:2007-08-01
修稿时间:2007-08-01

Clinical and pathological analyses of estrogan receptor and progestin recetor expressions in metachronous bilateral breast cancer
ZHONG Hong,MA Bin-ling,WANG Wei. Clinical and pathological analyses of estrogan receptor and progestin recetor expressions in metachronous bilateral breast cancer[J]. Journal of Xinjiang Medical University, 2007, 30(11): 1251-1253
Authors:ZHONG Hong  MA Bin-ling  WANG Wei
Abstract:Objective:To investigate estrogen and progestin recepto(ER and PR) expressions in metachronous bilateral breast cancer.Methods:ER and PR expressions in 25 cases of metachronous bilateral breast cancer from 2002 to 2006 and pathological features were analyzed retrospectively.Results:ER-and PR-positive expressions were 68% and 56% in first primary cancer of metachronous bilateral breast cancer,and 60% and 40% in second primary cancer of metachronous bilateral breast cancer.Respectively Invasive ductaltype carcinoma was 64% in first cancer of metachronous bilateral breast cancer and 52% in second primary cancer of metachronous bilateral breast cancer.Conclusion:There is higher ER and PR expression in metachronous bilateral primary breast cancer.Invasive ductaltype carcinoma is significantly related to the metachronous bilateral breast cancer.
Keywords:bilateral breast cancer   ER   PR
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