左心耳在预测心房颤动发生脑卒中的作用

成为公共健康沉重负担的心房颤动和相关的血栓栓塞性脑卒中事件仍在以惊人的速度增长。心房颤动导致脑卒中的风险增加了5倍．．因此，预防脑卒中的心房颤动管理仍然是最关键的一方面。现在公认的重点预防措施就是规范抗凝，包括已使用很广泛的华法林和现在出现的新抗凝药如利伐沙班等。而且抗凝药的使用已有据可查。由于左心耳在心房鲡动血栓的发生中起关键作用，所以有目的性地去除或结扎左心耳来预防发生脑卒中就成了一种可替代的治疗方法，尤其是适用于那些不适合口服抗凝药的患者，，现就左心耳预测心房颤动发生脑卒中进行介绍。

The Effect of Left Atrial Appendage in Predicting Stroke in Atrial Fibrillation

The public health burden of atrial fibrillation and associated thromboembolic stroke continues to grow at alarming rates. At rial fibrillation leads to a five-fold increase in the risk of stroke. Therefore, stroke prevention remains the most critical aspect of atrial fibrilla tinn management. Current standard of c, are focuses on oral systemic anticoagulation, most commonly with warfarin and now with newer agents such as rivaroxaban. However, the challenges and limitations of oral anticoagulation have been well documented. Given the eritical role of the left atrial appendage in the genesis of atrial fibrillation-related thromboembolism, recent efforts have targeted removal or occlusion of the left atrial appendage as an alter native strategy for stroke prevention, particularly in patients deemed unsuitable for oral anticoagulatinn.