Multiple pulmonary nodules after recovery from chickenpox in a patient with chronic lymphocytic leukaemia |
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| Authors: | YOSHIHIRO MIYASHITA,HIROAKI KOIKE,AKIHIKO MISAWA,HIDEAKI SHIMIZU,KAZUNORI YOSHIDA,TAKASHI YASUTOMI,NOBUYUKI KANAI,& TOSHIHIDE KAGAMI |
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| Affiliation: | Department of Internal Medicine, Shiokawa Hospital, Yamanashi-ken;Department of Surgery, Shiokawa Hospital, Yamanashi-ken;Department of Orthopedic Surgery, Shiokawa Hospital, Yamanashi-ken;Department of Pathology, Jichi Medical School, Tochigi-ken, Japan |
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| Abstract: | ![]()
Abstract A 61-year-old woman with chronic lymphocytic leukaemia (CLL) was found to have multiple pulmonary nodules on an annual chest radiograph 4 months after recovery from chickenpox. To exclude the metastatic carcinoma, an open lung biopsy was performed. Histological examination disclosed isolated necrotic nodules surrounded by some lymphocytes and a few giant cells. These histological findings were compatible with healed varicella pneumonia and the DNA of varicella-zoster virus (VZV) was detected by polymerase chain reaction (PCR) method. We report a case of asymptomatic pulmonary involvement of VZV infection in a patient with CLL. |
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| Keywords: | polymerase chain reaction varicella pneumonia |
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