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肠益方对湿热蕴结型大肠癌术后患者免疫功能的影响
引用本文:程悦蕾,朱惠蓉,邹菁,柴妮,李绪德.肠益方对湿热蕴结型大肠癌术后患者免疫功能的影响[J].中医药学刊,2014(10):2486-2488.
作者姓名:程悦蕾  朱惠蓉  邹菁  柴妮  李绪德
作者单位:上海中医药大学附属曙光医院,上海200021
基金项目:上海市科学技术委员会基金项目(09dz1974200); 上海市重点学科(第3期)建设经费项目(S30302)
摘    要:目的:观察肠益方对湿热蕴结型大肠癌术后患者免疫功能的影响。方法:将140例大肠癌术后患者随机分为,治疗组102例,其中湿热夹瘀者49例,湿热兼虚者53例;对照组38例。对各组治疗前后免疫功能(CD3+,CD4+,CD8+,CD4+/CD8+,NK)予以观察对比。结果:治疗后各组的CD4+数值均增高,CD8+数值均降低,CD4+/CD8+的比值均增高,均有显著差异(P〈0.01)。治疗后治疗湿热夹瘀组及治疗湿热兼虚组CD3+数值增高,有显著差异(P〈0.05)。各组间比较无明显统计学差异(P〉0.05)。结论:肠益方对大肠癌术后患者,能够一定程度的改善患者的免疫功能,且疗效与对照组相当。

关 键 词:大肠癌  肠益方  免疫功能

Immune Function Influence of Changyi Formula in Treatment of Damp- heat Type Patients with Colorectal Cancer
CHENG Yuelei,ZHU Huirong,ZHOU Jing,CHAI Ni,LI Xude.Immune Function Influence of Changyi Formula in Treatment of Damp- heat Type Patients with Colorectal Cancer[J].Study Journal of Traditional Chinese Medicine,2014(10):2486-2488.
Authors:CHENG Yuelei  ZHU Huirong  ZHOU Jing  CHAI Ni  LI Xude
Institution:(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China)
Abstract:Objective: This test aims that through clinical research and observation of Changyi Formula to treat damp-heat type patients with colorectal cancer and to observe the influence of immune function. Methods: This test collected 140 patients. They were randomly divided into treatment group and control group,and were given treatment of Changyi Formula or Pingxiao Capsule for three months. We gathered the information of immune function markers(CD3+,CD4+,CD8+,CD4+/CD8+,NK) before and after the treatment. Results: Comparing the treated group with the controlled group,there was significant difference(P〈0. 01,P〈0. 05) in the immune function markers( CD3+,CD4+,CD8+,CD4+/CD8+) in damp- heat type patients with colorectal cancer before and after treatment. And the treatment group and control group had no difference(P〈0. 05). Conclusion: Changyi Formula can improve the immune function in damp- heat type patients with colorectal cancer. And the treatment group and control group had the same clinical curative effect.
Keywords:colorectal cancer  Changyi Formula  immune function
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