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Holographic coherent anti-Stokes Raman scattering bio-imaging |
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| Authors: | Shi Kebin Edwards Perry S Hu Jing Xu Qian Wang Yanming Psaltis Demetri Liu Zhiwen |
| Affiliation: | 1Department of Electrical Engineering, The Pennsylvania State University, University Park, PA 16802, USA;2State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing 100871, China;3Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA;4School of Engineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland |
| Abstract: | CARS holography captures both the amplitude and the phase of a complex anti-Stokes field, and can perform three-dimensional imaging by digitally focusing onto different depths inside a specimen. The application of CARS holography for bio-imaging is demonstrated. It is shown that holographic CARS imaging of sub-cellular components in live HeLa cells can be achieved. |
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