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| 心肌乏氧显像及其临床应用 | |
| 引用本文： | 张弘,蒋宁一. 心肌乏氧显像及其临床应用[J]. 国际放射医学核医学杂志, 2004, 28(3): 113-117 |
| 作者姓名： | 张弘 蒋宁一 |
| 作者单位： | 510120 广州, 中山大学附属第二医院核医学科 |
| 摘 要： | 心肌乏氧显像是通过评价心肌氧供与氧耗平衡而提供检测缺血但存活心肌的一种非侵入性检查方法,而且是评价血管生成及心肌病的发生和发展的有用指标。动物实验和已有的临床研究表明,18F标记的硝基咪唑类化合物、有广泛应用前景的99Tcm标记的咪唑类化合物以及其他新的乏氧显像剂已用于评价缺血存活心肌。广泛的临床应用有待于进一步实验及临床研究。 |
| 关 键 词： | 心肌乏氧显像 乏氧显像剂 临床应用 |
| 文章编号： | 1001-098X(2004)03-0113-05 |
| 收稿时间： | 2003-09-22 |
| 修稿时间： | 2003-09-22 |
Myocardial hypoxia imaging and clinical application |
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| ZHANG Hong,JIANG Ning-yi. Myocardial hypoxia imaging and clinical application[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2004, 28(3): 113-117 | |
| Authors: | ZHANG Hong JIANG Ning-yi |
| Affiliation: | Department of Nuclear Medicine, The Second Affiliate Hospital of Sun Yat-sun University, Guangzhou 510120, China |
| Abstract: | Myocardial hypoxia imagings provide noninvasive approaches for the detection of myocardial ischemia, dedication of the potential role of hypoxia in development of angiogenesis and cardiomyopathy by the detection of balance of flow and oxygen consumption. Animal experiments and clinical trials show fluoromisonidazole and technetium-99m labeled nitroimidazoles and novel class hypoxia imaging markers have been developed for imaging of regional myocardial ischemia. The true clinical applications rely on future experimental and clinical studies. |
| Keywords: | myocardium hypoxia imaging clinical application |
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