连续性肾脏替代与间歇性血液透析治疗急性肾功能衰竭的生存率分析

目的 探讨连续性肾脏替代与间歇性血液透析治疗急性肾功能衰竭的生存率分析.方法 按照纳入标准搜集国内运用连续性肾脏替代和间歇性血液透析对比治疗急性肾功能衰竭的文献.使用Rev Man 5.0统计软件完成Meta分析,以SAS 8.0软件计算失安全系数.结果 按照纳入标准及排除标准,最后纳入6篇文献,包括受试患者476例进...

Survival rate of intermittent versus continuous renal replacement therapy for acute renal failure

Objective To evaluate survival rate of Intermittent versus continuous renal replacement therapy for acute renal failure. Methods Chinese studies which meet inclusion criteria were sought, compared CRRT with IHD therapy for acute renal failure. Meta-analysis was processed by Rev Man 5.0, fail-safe number (was performed by SAS 8.0). Results Six studies involving 476 patients, met the inclusion criteria, were included in the Meta analysis. The baseline of patients' characteristics was comparable in all the studies. By comparing the three criteria, including BUN, Scr and mortality, we found that no different efficacy and mortality between CRRT and IHD. Conclusions Our data suggest that CRRT and IHD are the effective choice in the treatment of severe ARF patients. In comparison to IHD therapy, CRRT does not improve prognosis or survival in patients with ARF. Because of few studies and small samples, higher quality trials with large samples and longer following-up are proposed.