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2型糖尿病患者骨密度的改变与白细胞介素-6和一氧化氮关系的探讨
引用本文:王艳军 李莉 沈静雪 刘英敏. 2型糖尿病患者骨密度的改变与白细胞介素-6和一氧化氮关系的探讨[J]. 中国骨质疏松杂志, 2002, 8(3): 213-215
作者姓名:王艳军 李莉 沈静雪 刘英敏
作者单位:1. 110004,沈阳,中国医科大学第二临床学院内分泌科
2. 沈阳市中心医院内科
摘    要:
目的 探讨2型糖尿病患骨密度、IL-6和NO变化及其IL-6和NO与骨密度的关系。方法 观察2型糖尿病组,正常对照组骨密度,IL-6和NO的变化并进行比较。分析2型糖尿病组中IL-6和NO与骨密度的关系。结果 2型糖尿病患的骨密度低于对照组,IL-6,NO水平高于对照组;2型糖尿病患IL-6,NO水平与骨密度呈显的负相关。结论 2型糖尿病患的骨密度降低,IL-6和NO的其中起重要作用。

关 键 词:2型糖尿病 骨密度 白细胞介素-6 一氧化氮 骨质疏松症
修稿时间:2002-02-07

Changes of bone mineral density and its relationship with bone mineral density and interleukin-6,nitric oxide in patients with type 2 diabetes mellitus
WANG Yanjun,LI Li,SHEN Jingxue,et al.. Changes of bone mineral density and its relationship with bone mineral density and interleukin-6,nitric oxide in patients with type 2 diabetes mellitus[J]. Chinese Journal of Osteoporosis, 2002, 8(3): 213-215
Authors:WANG Yanjun  LI Li  SHEN Jingxue  et al.
Affiliation:WANG Yanjun,LI Li,SHEN Jingxue,et al.Department of Endocrinology,The Second Clinical College,China Medical University,Shenyang 110004,China,
Abstract:
Objective To investigate the changes of BMD, interleukin|6(IL|6)and nitric oxide(NO), and relationship between them in patients with diabetes mellitus(DM). Methods The changes of BMD and IL|6 and NO in type 2 DM group and normal group were observed,and the relationships between IL 6,NO and BMD were analyzed. Results BMD in DM group was lower than that in normal group,the levels of IL 6 and NO in DM group were higher than that in normal group.IL 6 and NO had negative correlation with BMD in DM group. Conclusion Type 2 DM patients have a lower BMD; IL|6 and NO play an important role in that occurrence.;
Keywords:Type 2 diabetes mellitus   Bone mineral density   Interleukin|6   Nitric oxide
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