右佐匹克隆片治疗癌症伴发失眠的疗效观察

目的：探讨右佐匹克隆片治疗癌症伴发失眠的疗效及安全性。方法：选取我院门诊及住院70例癌症伴发失眠的患者，随机分为研究组和对照组，观察2周，研究组给予右佐匹克隆片口服，对照组给予阿普唑仑片口服，在治疗前、治疗2周末给予PSQI[1]量表评定，不良反应采用TESS量表评定。结果：治疗2周末给予PSQI量表评定，2组日间功能障碍P〈O．05有显著的统计学差异，其它各项目评分P〉0．05无显著的统计学差异。右佐匹克隆片无宿醉效应，不良反应少。结论：右佐匹克隆片治疗癌症伴发失眠的患者疗效确切，不良反应较少，安全性高。

Observation on curative effect of dexzopiclon to treatment of cancer comorbid insomnia.

Objective： To explore the efficacy and safety of dexzopiclon in the treatment of cancer comorbid insomnia. Methods： Select 70 cases of of cancer comorbid insomnia of our hospital patient and outpatient, were randomly divided into research group and the control group, the patient group given dexzopiclon tablets, the control group given alprazolam tablets. Efficacies were assessed with PSQI and ad- verse reactions with TESS at baseline and at zhe end of zhe 2rid. Results：PSQI scales to assess of treatment 2 weekend, the difference of two groups of daytime dysfunction （ P 〈 0.05 ） were statistically significant, other project scores （ P 〉 0.05 ）, were no significant statisti- cal difference. Dexzopiclon tablet was no hangover effect, less adverse reaction. Conclusion： Dexzopiclon to treat cancer patients with in- somnia curative might show the exact curative effect, less adverse reaction, high safety.