Acute two-vessel coronary closure in a patient with Down's syndrome

Myocardial infarctions are rare in patients with Down's syndrome. This paper reports an unusually aggressive presentation of two-vessel simultaneous coronary occlusion during an intended percutaneous intervention. Since survival in patients with Down's syndrome is improving, encounters with late (and perhaps unusual) sequelae of coronary artery disease are expected to increase. (Int J Cardiovasc Intervent 2003; 5: 95-97)