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趋化因子与先兆子痫
引用本文:朱亚静,张文真. 趋化因子与先兆子痫[J]. 中国妇幼健康研究, 2006, 17(6): 484-486
作者姓名:朱亚静  张文真
作者单位:河北医科大学第二医院妇产科,河北,石家庄,050000;河北医科大学第二医院妇产科,河北,石家庄,050000
摘    要:趋化因子及其受体除在自身免疫及炎症反应发挥作用外,还可能是免疫反应的主要管理者,在妊娠局部免疫反应中发挥重要作用.在女性生殖活动中,趋化因子直接或间接通过影响白细胞作用于子宫内膜,参与胚胎着床、胎盘血管重铸、分娩等生理过程,在母胎免疫平衡失调性病理妊娠如先兆子痫、习惯性流产的发病机制中也起重要作用.

关 键 词:趋化因子  趋化因子受体  IL-8  先兆子痫
文章编号:1673-5293(2006)06-0484-03
收稿时间:2006-08-25
修稿时间:2006-08-25

Relationship between chemokines and preeclampsia
ZHU Ya-jing,ZHANG Wen-zhen. Relationship between chemokines and preeclampsia[J]. Chinese Journal of Maternal and Child Health Research, 2006, 17(6): 484-486
Authors:ZHU Ya-jing  ZHANG Wen-zhen
Affiliation:Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Hebei Medical University,Hebei Shijiazhuang 050000,China
Abstract:Chemokines and chemokine receptors have been payed close attention by many scholars in recent years.Scholars considered that they may be major immunoreactive regulators and play important roles during pregnancy in not only local immunity but also autoimmune and inflammatory reaction.Chemokines participate embryo nidation,placenta blood vessel recast,and delivery,by directly or indirectly influencing WBC,they effect on endometrium of the female. Chenmokines maybe also play important role in some pathologic pregnancies due to feto-maternal immune disequilibrium: such as preeclampsia and habitual abortion.
Keywords:chemokine  chemokine receptor  IL-8  preeclampsia
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