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A contribution to the formation mechanism of calcium oxalate urinary calculi |
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| Authors: | E. Hienzsch A. Hesse C. Bothor W. Berg J. Roth |
| Affiliation: | (1) Urological Clinic, Friedrich Schiller University, Jena, German Democratic Republic;(2) Institute of Pathology, Friedrich Schiller University, Jena, German Democratic Republic;(3) Out-patient Department of the Friedrich-Schiller University, Lessingstrasse 1, DDR-69 Jena, German Democratic Republic |
| Abstract: | Summary Rabbits were given glyoxylic acid to induce intrarenal calcium oxalate crystal formation. The point of crystallisation in the renal tubule, the structure and the composition of the intrarenal crystals were studied. The initial crystallisation takes place in the proximal tubule. Calcium phosphate formation was excluded by microprobe examination. The comparison of the structures of the intrarenally formed crystals with those of Whewellite stones by scanning electron microscopy and the examination of isolated crystals by x-ray diffraction showed the intratubular crystals to consist of Whewellite. |
| Keywords: | Urolithiasis Calcium oxalate Intrarenal crystallisation Scanning electron microscopy |
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