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| p38丝裂原活化蛋白激酶在肿瘤治疗中的作用 | |
| 引用本文： | 邹俊勇,周建英. p38丝裂原活化蛋白激酶在肿瘤治疗中的作用[J]. 国外医学:内科学分册, 2007, 34(3): 135-138 |
| 作者姓名： | 邹俊勇 周建英 |
| 作者单位： | 浙江大学医学院附属第一医院呼吸内科,浙江,杭州,310003;浙江大学医学院附属第一医院呼吸内科,浙江,杭州,310003 |
| 摘 要： | p38丝裂原活化蛋白激酶(p38MAPK)最早因为与应激相关而引起注意,近来发现它在多种肿瘤包括宫颈癌,卵巢癌,肝癌,淋巴瘤中,与凋亡的启动、细胞周期的静止等密切相关,并且具有细胞特异性,在不同肿瘤细胞作用并不相同,甚至起了完全相反的作用.因此,具体研究p38MAPK信号途径在各种肿瘤及正常细胞中的作用可为进一步的肿瘤治疗提供理论指导. |
| 关 键 词： | p38丝裂原活化蛋白激酶 肿瘤 治疗 |
| 文章编号： | 1004-2369（2007）03-0135-04 |
| 修稿时间： | 2006-06-302006-07-29 |
The role of p38MAPKS in cancer therapy |
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| ZOU Jun-yong,ZHOU Jian-ying. The role of p38MAPKS in cancer therapy[J]. Foreign Medical Sciences(Section of Internal Medicine), 2007, 34(3): 135-138 | |
| Authors: | ZOU Jun-yong ZHOU Jian-ying |
| Affiliation: | Dpartment of Respiratory Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou 310003, China |
| Abstract: | p38MAPKS pathway was traditionally associated with the stress pathway. More recently, it has been reported that the p38MAPKS pathway can also regulate the cell cycle and apoptosis in many kinds of carcinomas, such as uterine cervix cancer.ovarian cancer,liver cancer and lymphoma. In different cancer cells, it can lead to different or even antipodal results. Therefore, it would supply theoretical guidance in tumor therapy, if we could study the effect of p38MAPKS pathway in cancer and normal cells in detail. |
| Keywords: | p38MAPKS Cancer Therapy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |