| 基于系统生物学阐释中药药性理论科学内涵的研究思路与方法探讨 |
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| 引用本文： | 刘树民,卢芳. 基于系统生物学阐释中药药性理论科学内涵的研究思路与方法探讨[J]. 世界科学技术, 2008, 10(2): 12-16 |
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| 作者姓名： | 刘树民 卢芳 |
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| 作者单位： | 黑龙江中医药大学中医药研究院,哈尔滨150040 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | 本文通过分析近代中药药性理论研究中存在的问题,针对性地提出了应用系统生物学尤其是代谢组学方法,以研究机体生物标志物及其变化规律为主线,阐释中药药性理论科学内涵的具体思路与方法及其预期成果,并提示运用此方法建立中药性味实质及性效关联性研究技术平台的重要性.
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| 关 键 词： | 系统生物学 代谢组学 中药药性理论 生物标志物 |
Technical Lines and Methods:Studying Scientific Connotations of Traditional Chinese Medicines Using Systems Biology |
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| Liu Shumin Lu Fang. Technical Lines and Methods:Studying Scientific Connotations of Traditional Chinese Medicines Using Systems Biology[J]. World Science and Technology(Modernization of Traditional Chinese Medicine), 2008, 10(2): 12-16 |
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| Authors: | Liu Shumin Lu Fang |
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| Affiliation: | Liu Shumin Lu Fang (Institute of Traditional Chinese Medicine,Heilongjiang University of Traditional Chinese Medicine,Heilongjiang,Harbin 150040) |
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| Abstract: | In this article,authors analyzed the existing issues concerning the study of TCM property theory in modern times. They proposed to study TCM property theory using systems biology,or metabolomics,in particular,making organic biomarkers and associated variations as the main line,and tracking down the anticipated outcome.Authors believe that it is important to establish a technical platform for studying the essence of the property,the flavor of traditional Chi- nese medicines,and property-effect correlation. |
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| Keywords: | systems biology metabolomics property theory of traditional Chinese medicine biomarkers |
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