2型糖尿病患者心律失常的临床特点分析

目的研究2型糖尿病患者合并心律失常情况及其临床特点。方法回顾性分析375例住院的2型糖尿病患者资料，根据心电图检查结果分为合并心律失常组（94例）和不合并心律失常组（28例）。对比分析两组患者的临床资料和心电图特点。结果心律失常总发病率为25％（94／375），以房性期前收缩发病率最高。2型糖尿病合并心律失常组原发性高血压（高血压），冠状动脉粥样硬化性心脏病（冠心病）发病率高于不合并心律失常组，差异有统计学意义[37．2％（35／94）US．32．7％（92／281），P〈O．05；7．4％（7／94）帆5．7％（16／281），P〈0．05]。Logistic回归分析显示，2型糖尿病患者的体质量，性别，年龄，血脂浓度，收缩压，糖尿病病程，疾病种类。劳动方式是发生心律失常的相关危险因素。结论2型糖尿病患者合并其他心血管疾病更容易发生心律失常．这可能与糖尿病病程、高血压、冠心病造成的心肌细胞，血管，自主神经系统受损有关。

Clinical characteristics of arrhythmias in patients with type 2 diabetes mellitus

Objectives To explore the clinical characteristics of arrhythmias in patients with type 2 diabetes mellitus.Methods Clinical data of 375 patients with type 2 diabetes mellitus were retrospectively analyzed.Accroding to arrhythmia detection by routine electrocardiography(ECG),the patients were divided into two groups:94 cases in arrhythmia group;281 cases in non-arrhythmia group.Data and ECG features of the two groups were analyzed and compared.Results Incidence rate of arrhythmia in 375 patients with type 2 diabetes was 25%(94/375),and the most common type among them was atrial premature beats.Incidence rates of hypertension and coronary heart disease in arrhythmia group were significantly higher than those in non-arrhythmia group [37.2%(35/94) vs.32.7%(92/281),P<0.05;7.4%(7/94) vs.5.7%(16/281),P<0.05].Logistic regression analysis showed that weight,gender,age,blood lipid levels,level of systolic pressure,diabetes duration,type of disease,mode of physical labor were relevant risk factors of arrhythmia.Conclusions Patients with type 2 diabetes melitus complicated with cardiovascular disease are easier to suffer from arrhythmia,which probably related to pathological changes of cardiac muscle cells,blood vessels and autonomic nerves caused by diabetes duration,hypertension and coronary heart disease.