前列腺增生并发膀胱结石形成原因探讨

目的初步探讨前列腺增生并发膀胱结石的形成原因。方法回顾性分析我院2003年1月至2010年12月收治的151例前列腺增生并发膀胱结石患者的临床资料。结果151例患者平均年龄71.8（50～93）岁,结石平均直径19（5～45）mm,前列腺体积平均44.8（23～231）mL,残余尿量〈20mL 95例（63%）,最大尿流率平均9.2（1～31.1）mL/s,有膀胱出口梗阻139例（92%）,合并尿路感染6例（4%）。结石成分主要为草酸钙102例（67%）、尿酸39例（26%）、碳磷灰石10例（7%）。结论草酸钙是前列腺增生并发膀胱结石中最常见的结石成分,与肾结石成分相似,而且大部分患者残余尿量较少,因此我们推测前列腺增生并发膀胱结石的形成机制中除膀胱出口梗阻外,可能还包括其他的理化及代谢因素。

Study of the causes of benign prostatic hyperplasia combined with bladder calculi

Objective To study the causes of benign prostatic hyperplasia combined with bladder calculi.Methods We retrospectively reviewed the clinical data of 151 patients who underwent surgical therapy for benign prostatic hyperplasia combined with bladder calculi in our hospital during Jan.2009 to Dec.2010.Results The mean a ge of patients was 71.8(ranging 45 to 93) years,the mean size of the stone 19(ranging 5 to 45) mm,mean prostatic volume 44.8(ranging 23 to 231) mL,mean maximum flow rate 9.2(ranging 1 to31.1) mL/s.95 patients(63%) had postvoid residual volume<20 mL,139 patients(92%) had bladder outlet obstruction caused by enlarged prostate,and 6 patients(4%) had urinary tract infections.The stone composition was as follows:calcium oxalate in 102 patients(67%),uric acid in 39 patients(26%) and calcium phosphate in10 patients(7%).Conclusions Calcium oxalate was the ma jor composition of bladder calculi.Most patients had little postvoid residual volume.Bladder outlet obstruction caused by enlarged prostate might be one of the causes of bladder calculi besides physicochemical and metabolic factors.