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| 假蒟化学成分的研究 | |
| 引用本文： | 李清,瞿发林,谭兴起,周伟杰,楼欣誉. 假蒟化学成分的研究[J]. 中成药, 2020, 0(7): 1799-1802 |
| 作者姓名： | 李清 瞿发林 谭兴起 周伟杰 楼欣誉 |
| 作者单位： | 中国人民解放军联勤保障部队第904医院;南京中医药大学翰林学院;常州卫生高等职业技术学校 |
| 基金项目： | 原南京军区重大专项课题(15DX005)。 |
| 摘 要： | 目的研究假蒟Piper sarmentosum Roxb.的化学成分。方法假蒟80%乙醇提取物乙酸乙酯萃取部位采用硅胶柱、Sephedex LH-20、TLC和重结晶等进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到8个化合物,分别鉴定为sesamin(1)、pellitorine(2)、1-nitrosoimino-2,4,5-trimethoxybenzene(3)、N-(3-phenylpropanoyl) pyrrole(4)、3-(4′-methoxyphenyl)propanoyl pyrrole(5)、β-sitosterol(6)、piperumbellactam A(7)、6,7-dimethoxy-4-hydroxy-1-naphthoic acid(8)。结论化合物5、7～8为首次从该植物中分离得到。 |
| 关 键 词： | 假蒟 化学成分 分离鉴定 |
Chemical constituents from Piper sarmentosum |
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| Affiliation: | (The 904th Hospital of Joint Logistic Support Force of PLA,Changzhou 213003,China;Hanlin College of Pharmacy,Nanjing University of Traditional Chinese Medicine,Taizhou 225300,China;Changzhou Hygiene Vocational Technology College,Changzhou 213003,China) |
| Abstract: | AIM To study the chemical constituents from Piper sarmentosum Roxb.METHODS The ethyl acetate fraction of 80%ethanol extract from P.sarmentosum was isolated and purified by silica,Sephedex LH⁃20,TLC and recrystallization,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Eight compounds were isolated and identified as sesamin(1),pellitorine(2),1⁃nitrosoimino⁃2,4,5⁃trimethoxybenzene(3),N⁃(3⁃phenylpropanoyl)pyrrole(4),3⁃(4′⁃methoxyphenyl)propanoyl pyrrole(5),β⁃sitosterol(6),piperumbellactam A(7),6,7⁃dimethoxy⁃4⁃hydroxy⁃1⁃naphthoic acid(8).CONCLUSION Compounds 5,7⁃8 are isolated from this plant for the first time. |
| Keywords: | Piper sarmentosum Roxb. chemical constituents isolation and identification |
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