米索前列醇联合丙泊酚麻醉在人工流产术中的效果观察

目的:观察米索前列醇用于无痛人工流产术前的临床效果及安全性。方法:分试验组、对照组,将50例妊娠50～70 d要求行无痛人工流产术的妇女年龄随机分成两组,试验组25例,术前2h舌下含化米索前列醇400μg;对照组25例不用米索前列醇,两组均在丙泊酚静脉麻醉下行人工流产。结果:观察组与对照组镇痛效果比较,差异无统计学意义(P>0.05),不良反应均较轻,而宫颈软化情况、术中出血量、及手术时间比较,差异有统计学意义(P<0.05)。结论:米索前列醇配合无痛人工流产术应用可使宫颈软化,一般无需扩宫,减少手术步骤,缩短手术时间,减少麻醉药用量及其不良反应,促进子宫收缩,减少术中出血,联合应用效果极佳,值得临床推广应用。

Observation of effects of misoprostol combined with propofol anesthesia in induced abortion

Objective To observe the clinical efficacy and safety of misoprostol used before painless induced abortion.Method 50 women pregnant for 50~70 days requiring painless induced abortion were randomized in two groups.In the test group,25 women sublingually took 400μg misoprostol at 2h before induced abortion;while in the control group,25 women did not use misoprostol,and the both groups underwent induced abortion under intravenous propofol anesthesia.Results The difference in analgesic effect between the test group and the control group had no statistical significance(P>0.05) and adverse reactions in both groups were mild,while the differences in cervical softening,intraoperative bleeding and surgery time between the two groups had statistical significance(P<0.05).Conclusion Misoprostol used for painless induced abortion can soften cervix without expanding palace,reduce surgical steps and time,reduce anaesthetic dosage and its adverse reactions,promote uterine contraction and reduce intraoperative bleeding,and its combined application has extremely good effects,so it is worth promoting.