131I对分化型甲状腺癌治疗后的疗效分析

目的：对分化型甲状腺癌（differentiated thyroid carcinoma，DTC）病人采用放射性碘（131I）治疗，从而评价131I治疗DTC的疗效。方法：收集2007～2013a在内蒙古医科大学附属医院经病理确诊的DTC病人50例，男性19例，女性31例，年龄24～77岁，平均51．28±15．43岁。其中，PTC28例，FTC22例。术后单纯发现颈部转移23例，肺转移3例，骨转移2例。结果：PTC组痊愈率75．0％，好转率14．3％，无效率7．1％，死亡率3．6％；FTC组痊愈率59．1％，好转率27．3％，无效率9．1％，死亡率4．5％。经统计学分析，χ2=23．93，P〈0．001，差异有统计学意义。术后单纯发现颈部转移23例，肺转移3例，骨转移2例，经统计学分析，χ2=18．36，P〈0．001，差异有统计学意义。结论：131I治疗DTC有较好的疗效，且PTC组治疗痊愈率高于FTC组，131I治疗疗效与转移灶部位有关，颈部转移灶治疗效果好于肺转移及骨转移。

THE CLINICAL ANALYSE OF RADIOIODINE EFFICACY OF DIFFERENTIATED THYROID CARCINOMA

Objective： To evaluate the effect of radioiodine treatment of differentiated thyroid carcinoma（DTC）. Methods： We collected the 50 patients with DTC by pathology at the Affiliated Hospital of Inner Mongolia Medical University from 2007 to 2013. Patients were ranging in age from 24 to 77 years （ mean 51.28±15.34） , men 19, women 31. There were 28 cases of PTC,22 cases of FTC. There were neck metastasis in 23 cases, lung metastasis in 3 cases, and bone metastasis in 2 cases. Results：The recovery rate in PTC group was 75.0% ,the remission rate 14.3% ,the inefficiency rate 7.1% ,and the mortality rate 3.6%. The recovery rate in FTC group was 59.1% , the remission rate 27.3 %, the inefficiency rate 9.1%, and the mortality rate 4.5 %. By statistical analysis, χ2 = 23.93, P〈0.001 ,the difference was statistically significant. There was also statistically significant in neck metastasis,lung metastasis and bone metastasis. Conclusions： Radioiodine treatment for DTC had a good effect. The treatment of PTC is the better than FTC. The therapeutic effect was related to the metastasis. The therapeutic effect of cervical metastasis was better than that of lung and osseous metastasis, and lung metastasis was better than osseous metastasis.