鲍曼不动杆菌感染分布及耐药性分析

目的：了解我院鲍曼不动杆菌的感染分布与耐药情况，为临床治疗提供依据。方法：对住院病人送检样本中培养分离出的825株鲍曼不动杆菌的感染分布与耐药情况进行分析。采用稀释法进行药物敏感试验，结果按CLSI标准判定。结果：鲍曼不动杆菌主要分布在重症监护病房（ICU）和呼吸科，主要来自痰标本（90.6%），对丁胺卡那霉素的耐药率最低（16.28%），其次为亚胺培南（31.25%），对其他19种抗菌药物的耐药率均较高。结论：鲍曼不动杆菌主要引起呼吸道感染，对现有多种抗菌药物耐药严重，提示临床医师必须对该菌所致感染予以高度重视。

ANALYSIS OF INFECTION DISTRIBUTION AND DRUG RESISTANCE OF ACINETOBACTER BAUMANNII

Objective：To investigate the clinical distribution and drug resistance of Acinetobacter baumannii in order to offer basis for the clinical therapeutics. Methods：Analyze the infection distribution and drug resistance of 825 samples of Acinetobacter baumannii that were isolated from various kinds of specimens from inpatients. The drug sensitivity test was done by means of dilution,and then the results were assessed with CLSI （ Clinical and Laboratory Standards Institute ） . Results：Acinetobacter baumannii samples were mainly distributed in ICU ward and Respiration department. The highest positive rate of Acinetobacter baumannii was in sputum （ 90 . 6%） . The resistance rates to Amikacin（16.28%）. were the lowest,and to Imipenem（31.25%）came to be next. Acinetobacter baumannii were high resistant to other 19 tested antibiotics. Conclusions：Acinetobacter baumannii is a common pathogen of respiratory tract infection,which has a high resistance rate to the current clinical antibacterial agents. Consequently, clinical doctors should attach more importance to the infection resulted from Acinetobacter Baumannii.